The Fifth Edition has been completely updated to reflect the many advancements that have been made in pulmonary medicine over the past few years, including:
- Molecular development of the lung
- Stem cells and respiratory disease
- Genetics of pulmonary disease and the growth of personalized medicine
- Technical advances in lung transplantation
- Growth in immunology and immunosuppressive management
- Diagnosis and treatment of pulmonary hypertension
- Circadian rhythms and sleep biology
- Rapid evolution in lung imaging techniques, including functional imaging
- Contemporary interventional bronchoscopic techniques
You will also find state-of-the-art coverage of the latest topics in critical care medicine, including:
- Early diagnosis and management of sepsis
- Multiple organ dysfunction syndrome (MODS)
- Acute respiratory distress syndrome (ARDS)
- Management of agitation and delirium in the ICU
- The newly defined entity of "chronic critical illness"

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