This is a comprehensive haematology text book. Very useful for clinical and Lab haematologists, trainees and lab scientists
Table of contents :Contents……Page 5
Contributors……Page 8
Preface to the fifth edition……Page 12
Preface to the first edition……Page 13
Introduction……Page 15
The stromal microenvironment……Page 16
Organization of haemopoiesis……Page 17
Haemopoietic growth factors and receptors……Page 21
Clinical applications of stem cell research……Page 24
Selected bibliography……Page 25
The origins of blood during development……Page 27
Differentiation of haemopoietic stem cells to form erythroid progenitors……Page 28
The transcription factor programme underlying erythropoiesis……Page 30
Terminal maturation of committed erythroid cells……Page 31
Changes in the cell surface phenotype that accompany erythroid differentiation and maturation……Page 32
Changes in gene expression in erythroid differentiation and maturation……Page 33
Sensing hypoxia……Page 34
Erythropoietin and the erythropoietin receptor……Page 35
Erythropoiesis in clinical practice……Page 37
Selected bibliography……Page 39
Distribution of body iron……Page 40
Cellular iron homeostasis……Page 43
Iron absorption……Page 44
Internal iron exchange……Page 46
Haem synthesis……Page 47
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